Subunit Composition Determines the Single Channel Kinetics of the Epithelial Sodium Channel

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Subunit Composition Determines the Single Channel Kinetics of the Epithelial Sodium Channel

We have further characterized at the single channel level the properties of epithelial sodium channels formed by coexpression of alpha with either wild-type beta or gamma subunits and alpha with carboxy-terminal truncated beta (betaT) or gamma (gammaT) subunits in Xenopus laevis oocytes. alphabeta and alphabetaT channels (9.6 and 8.7 pS, respectively, with 150 mM Li+) were found to be constitut...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1998

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.112.4.423